Status:

COMPLETED

Clearing the Fog: Is Hydroxychloroquine Effective in Reducing COVID-19 Progression

Lead Sponsor:

UNICEF

Collaborating Sponsors:

Pak Emirates Military Hospital

Conditions:

Covid19

Progression

Eligibility:

All Genders

18-80 years

Phase:

PHASE3

Brief Summary

Brief Summary: Purpose of this study is to evaluate efficacy of hydroxychloroquine (HCQ) in reducing progression of Corona Virus Disease 2019 (COVID - 19) and achieving viral clearance. Condition or ...

Detailed Description

This study explores efficacy of HCQ (400mg BD on D0 and 200mg BD D1-D5) in reducing progression of Mild Covid-19 patients and decreasing viral load. Participants of study will be randomized 2:1 to re...

Eligibility Criteria

Inclusion

  • Mild Corona virus disease (COVID-19)
  • PCR confirmed infection
  • Hospital admitted patients

Exclusion

  • Moderate, severe and critical COVID-19
  • day 0 CRP greater than 6mg/dl, ALC \< 1000 or evidence of infiltrates on X-ray chest
  • comorbidity with life expectancy less than 6 months
  • Contraindications to HCQ therapy

Key Trial Info

Start Date :

April 10 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 31 2020

Estimated Enrollment :

540 Patients enrolled

Trial Details

Trial ID

NCT04491994

Start Date

April 10 2020

End Date

May 31 2020

Last Update

August 21 2020

Active Locations (1)

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Pak Emirates Military Hospital

Rawalpindi, Punjab Province, Pakistan, 46000