Status:
UNKNOWN
Conjunctival Vascularity Changes Usnig OCTA After Trabeculectomy
Lead Sponsor:
Asmaa Ahmed Ali Youssif
Conditions:
OCTA
Eligibility:
All Genders
18-85 years
Phase:
EARLY_PHASE1
Brief Summary
* Reduce the trauma and the time taken for patient rehabilitation. * The prevailing trend is to perform a mitomycin- C (MMC)-augmented trabeculectomy and trabeculectomy with ologen implants in a trial...
Detailed Description
The main purpose of this project is to compare bleb vascularity changes using optical coherence tomography (OCT-A) between mitomycin- C (MMC)-augmented trabeculectomy and develop trabeculectomy with o...
Eligibility Criteria
Inclusion
- patients older than 18 years of age with primary or secondary open-angle glaucoma.
- Primary OAG (POAG) diagnosed on the basis of IOP measurements more than 21 mmHg, open angle on gonioscopy (Grade 3 or 4 on Schaffer grading system for angle width), glaucomatous visual field defects consistent with glaucomatous optic disc changes.
- PNAG was diagnosed by the presence of narrow or occludable angle on gonioscopy (Grade 2, or 1 on Schaffer grading system for angle width in at least 180° of the total circumference of the angle in primary position without indentation), glaucomatous optic disc changes, visual field defects and IOP more than 21 mmHg
Exclusion
- pregnant or lactating female.
- previous intraocular surgery
- one-eyed patients.
- previous ocular trauma.
- uveitis-induced glaucoma, neovascular glaucoma, aphakic/pseudophakic glaucoma
- systemic connective tissue disease and missing more than 3 follow-up visits.
- Trabeculectomy augmented by either MMC or Ologen implant was indicated to study subjects if they had uncontrolled IOP under maximum antiglaucoma medications (3 antiglaucoma drugs) or due to poor socioeconomic status.
Key Trial Info
Start Date :
December 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 1 2022
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04493073
Start Date
December 1 2020
End Date
March 1 2022
Last Update
July 30 2020
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