Status:

COMPLETED

A Study of LY3041658 in Adults With Hidradenitis Suppurativa

Lead Sponsor:

Eli Lilly and Company

Conditions:

Hidradenitis Suppurativa

Eligibility:

All Genders

18-65 years

Phase:

PHASE2

Brief Summary

The reason for this study is to see if the study drug LY3041658 is effective in participants with moderate-to-severe hidradenitis suppurativa (HS).

Eligibility Criteria

Inclusion

  • Have a diagnosis of HS for at least 6 months
  • Have HS lesions in at least 2 different anatomic areas
  • Have inadequate response or intolerance to a 28 day course of oral antibiotics
  • Have a total count of abscesses and inflammatory nodules greater than or equal to 4
  • Agree to use a topical antiseptic daily
  • Agree to stop using topical antibiotics during the study. In certain cases, oral antibiotics will be allowed

Exclusion

  • Have more than 20 draining fistulae
  • Have received any biologic medication (adalimumab, etc.) for the treatment of HS
  • Plan to use oral opioids for HS-related pain during the study
  • Uncontrolled depression or suicidal thoughts

Key Trial Info

Start Date :

August 26 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 13 2022

Estimated Enrollment :

72 Patients enrolled

Trial Details

Trial ID

NCT04493502

Start Date

August 26 2020

End Date

October 13 2022

Last Update

April 28 2023

Active Locations (20)

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Page 1 of 5 (20 locations)

1

Northwest Arkansas Clinical Trials Center

Rogers, Arkansas, United States, 72758

2

First OC Dermatology

Fountain Valley, California, United States, 92708

3

Dermatology Research Associates

Los Angeles, California, United States, 90045

4

Skin Care Research, Inc

Hollywood, Florida, United States, 33021