Status:
UNKNOWN
Liver Fibrosis and Gut Microbiota in Patients With Psoriasis Vulgaris and Rheumatoid Arthritis on Methotrexate
Lead Sponsor:
The University of Hong Kong
Conditions:
Psoriasis Vulgaris
Rheumatoid Arthritis
Eligibility:
All Genders
18-85 years
Brief Summary
While methotrexate (MTX) remains a treatment of choice for patients with rheumatoid arthritis (RA), psoriasis (PsO) and psoriatic arthritis (PsA), long-term MTX use has been shown to be associated wit...
Eligibility Criteria
Inclusion
- Age between 18 to 85 years
- Have regular follow up in Dermatology/ Rheumatology clinics of Queen Mary Hospital
- Diagnosed with PsO/PsA or RA
- Chinese ethnicity
Exclusion
- Age below 18 years or above 85 years
- Known decompensated cirrhosis
- Pregnancy or breastfeeding
- Unstable medical illness or active infection
- Unable to provide written consent
- Unable to adhere to the protocol
- Unable to read and/or write Chinese language
- On anticoagulant/ antiplatelet treatment
- Abnormal platelet count \<150
- Known disease/condition with prolonged INR/bleeding tendency
Key Trial Info
Start Date :
August 13 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 11 2022
Estimated Enrollment :
600 Patients enrolled
Trial Details
Trial ID
NCT04493762
Start Date
August 13 2020
End Date
December 11 2022
Last Update
July 30 2020
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