Status:

UNKNOWN

Evaluation of Eosinophil Phenotype in COPD Patients

Lead Sponsor:

IRCCS San Raffaele Roma

Conditions:

COPD

COPD Exacerbation

Eligibility:

All Genders

18+ years

Brief Summary

This is a pilot non pharmacological observational study. Aim of the study is to analyze the immunophenotype of circulating eosinophils in chronic obstructive pulmonary disease (COPD) patients, and to ...

Detailed Description

In about 30% of COPD patients there is an increased number of circulating eosinophils. On their membrane, eosinophils express several molecules, also related to their physiology, namely major histocom...

Eligibility Criteria

Inclusion

  • COPD
  • percentage of eosinophils \>0%
  • episode of exacerbation in the previous 10 days (for exacerbated cohort)
  • no exacerbation in the previous 3 months (for stable cohort)

Exclusion

  • percentage of eosinophils =0%
  • history of allergic diseases
  • patients that are currently enrolled in other clinical trials involving new drugs or treatments

Key Trial Info

Start Date :

March 19 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

July 1 2025

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT04494308

Start Date

March 19 2019

End Date

July 1 2025

Last Update

April 10 2024

Active Locations (1)

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1

IRCCS San Raffaele Pisana

Roma, RM, Italy, 00166