Status:

COMPLETED

Qualitative Understanding of Community TB Services Pre and Post the CHIP-TB Trial

Lead Sponsor:

Johns Hopkins University

Collaborating Sponsors:

UNITAID

Aurum Institute

Conditions:

Tuberculosis Infection

Tuberculosis Prevention

Eligibility:

All Genders

18+ years

Brief Summary

This qualitative study is designed to elicit the perspectives of relevant stakeholders to adapt a community-based TB/HIV intervention aimed on providing home-based TB prevention treatment (TPT) initia...

Detailed Description

Tuberculosis (TB) remains a top 10 cause of child mortality in sub-Saharan Africa. Short-course combination TB preventive therapy (TPT) regimens are highly effective with high completion rates and the...

Eligibility Criteria

Inclusion

  • Inclusion Criteria for Interview 1:
  • Adult caregiver (18 years of age or older) of a child (\<15 years of age) who was exposed to TB in the last two years where at least one child was evaluated for and offered either TB preventive therapy or TB treatment.
  • or
  • Community health team members from one of the Ethiopian or South African clinics in which the CHIP-TB trial will be conducted.
  • or
  • TB nurse from one of the 16 Ethiopian or South African clinics in which the study will be conducted
  • or
  • Pediatrician or medical officer working in pediatrics at the relevant Ethiopian or South African District Hospital who sees outpatient pediatric consultations including TB-exposed children
  • or
  • Program manager or policy maker in the relevant Ethiopian or South African district or provincial office who manages TB, PMTCT, and/or other pediatric programming
  • Exclusion Criteria for Interview 1:
  • Any adult caregivers, community health team members, TB nurses, medical officers or pediatricians, program managers or policy makers who are unable or unwilling to provide informed consent for both the interview and audio-recording
  • Inclusion Criteria for Interview 2:
  • Any community health team members, TB nurses, medical officers or pediatricians, program managers or policy makers who participated in the program for at least 3 months
  • Any adult caregiver whose child participated in the community-based TB prevention program
  • Exclusion Criteria for Interview 2:
  • Any adult caregivers, community health team members, TB nurses, medical officers or pediatricians, program managers or policy makers who are unable or unwilling to provide informed consent for both the interview and audio-recording

Exclusion

    Key Trial Info

    Start Date :

    June 4 2021

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    June 30 2023

    Estimated Enrollment :

    183 Patients enrolled

    Trial Details

    Trial ID

    NCT04494516

    Start Date

    June 4 2021

    End Date

    June 30 2023

    Last Update

    July 12 2023

    Active Locations (2)

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    Page 1 of 1 (2 locations)

    1

    KNCV Tuberculosis Foundation

    Addis Ababa, Ethiopia

    2

    The Aurum Institute

    Johannesburg, South Africa