Status:

COMPLETED

NGS Panel of Incomplete Forms of Ocular Albinism

Lead Sponsor:

University Hospital, Bordeaux

Conditions:

Albinism, Ocular

Eligibility:

All Genders

Brief Summary

Implementation of a next-generation sequencing panel of genes to identify deleterious variants in patients with incomplete forms of albinism.

Detailed Description

Scientific context : Albinism is clinically characterised by cutaneous hypopigmentation and ophthalmologic features. These features common to all forms of albinism are foveal hypoplasia, misrouting of...

Eligibility Criteria

Inclusion

  • Minor and adult patient.
  • Patient presenting a clinical diagnosis of incomplete form of albinism with presence of at least 2 signs of ocular albinism among which nystagmus, low vision, foveal hypoplasia, retinal hypopigmentation, translucent irides, misrouting of the optic nerves at the chiasm.
  • Registered for the social security system.
  • Informed consent signed by patient or parent of a minor patient.

Exclusion

  • Refusal to participate in research protocol.

Key Trial Info

Start Date :

November 23 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

February 28 2024

Estimated Enrollment :

53 Patients enrolled

Trial Details

Trial ID

NCT04495218

Start Date

November 23 2020

End Date

February 28 2024

Last Update

September 19 2024

Active Locations (1)

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Centre Hospitalier Universitaire de Bordeaux

Bordeaux, France