Status:

WITHDRAWN

Precision Medicine in Anesthesia

Lead Sponsor:

University of Alabama at Birmingham

Conditions:

Respiratory Depression

Eligibility:

All Genders

19-40 years

Brief Summary

This study is designed to look at how often a decrease in the rate of breathing occurs after being given a routinely used intravenous (IV) pain medication. This pain medication (Fentanyl) is given in ...

Detailed Description

Opioids are key analgesic drugs. Unfortunately, they have a high potential for abuse with potentially lethal consequences, more specifically death due to respiratory suppression. In both Canada and th...

Eligibility Criteria

Inclusion

  • Healthy Subjects
  • older than 19
  • able to follow the study instructions

Exclusion

  • Any medical condition that could affect study procedures or potentially put the subject at risk, in the opinion of the investigators
  • age less than 18 or older than 40
  • pregnancy
  • obesity
  • sleep apnea
  • pulmonary problems such as moderate or severe bronchial asthma
  • epilepsy
  • chronic analgesic medication
  • history of surgery for which details are unavailable
  • allergy to fentanyl
  • history of drug abuse
  • positive urine test for illicit drugs
  • female participants will be scheduled for a urine pregnancy test on the day of the procedure, prior to receiving study medication, only subjects with negative tests will continue

Key Trial Info

Start Date :

June 10 2024

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 1 2026

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT04495452

Start Date

June 10 2024

End Date

September 1 2026

Last Update

February 5 2025

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