Status:

RECRUITING

Ofloxacin Concentration-toxicity Relationship in the Elderly

Lead Sponsor:

Centre Hospitalier Universitaire, Amiens

Conditions:

Ofloxacin

Bone and Joint Infection

Eligibility:

All Genders

65+ years

Phase:

NA

Brief Summary

Ofloxacin is a gold standard antibiotic for the treatment of bone and joint infections due to sensible staphylococcus strains. However, in the elderly, inter-individual variability of the pharmacokine...

Eligibility Criteria

Inclusion

  • Patients aged over 65 years hospitalized at the University Hospital of Amiens for an uncomplicated bone and joint infections
  • Indication for oral switch to ofloxacin

Exclusion

  • Patient refusing to participate in the study
  • Patient under guardianship or curators or deprived of public rights
  • Any liver or biliary injury
  • Any contraindications to ofloxacin

Key Trial Info

Start Date :

June 2 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 1 2026

Estimated Enrollment :

110 Patients enrolled

Trial Details

Trial ID

NCT04496024

Start Date

June 2 2020

End Date

August 1 2026

Last Update

June 10 2025

Active Locations (1)

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1

CHU Amiens

Amiens, France, 80480