Status:

UNKNOWN

Effects of Prostaglandin E1 Treatment on Pyloric Wall in Newborns

Lead Sponsor:

Hacettepe University

Conditions:

Pyloric Stenosis;Acquired

Congenital Heart Disease

Eligibility:

All Genders

Up to 28 years

Brief Summary

Prostaglandin E1 (PGE1) has been used in the medical treatment of ductal dependent critical congenital heart disease in neonates. Apnea/ bradycardia, hypotension, hypokalemia, feeding difficulties, fe...

Detailed Description

Intravenous prostaglandin E1 infusion is referred to as ductus dependent diseases, in systemic (aortic blood flow) circulation (eg critical aortic coarctation, intermittent arcus aorta, hypoplastic le...

Eligibility Criteria

Inclusion

  • Newborn babies who are hospitalized in Hacettepe University Faculty of Medicine İhsan Doğramacı Children's Hospital Neonatal Intensive Care Unit and who are receiving prostaglandin E1 infusion due to PDA-dependent congenital heart disease.
  • Newborns who have the above criteria and whose consent form has been enlightened by their parents has been read and accepted to participate in the study.

Exclusion

  • Babies whose consent to participate in the study cannot be obtained.
  • Babies with chromosomal disease or hereditary metabolic disease
  • Babies who died during the first week of life and whose ultrasonography measurements could not be obtained.

Key Trial Info

Start Date :

May 6 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

November 30 2020

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT04496050

Start Date

May 6 2019

End Date

November 30 2020

Last Update

August 3 2020

Active Locations (1)

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Hacettepe University

Ankara, Turkey (Türkiye)