Status:

ENROLLING_BY_INVITATION

Focused Ultrasound for the Treatment of ADHD Symptoms

Lead Sponsor:

Neurological Associates of West Los Angeles

Conditions:

ADHD

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

The purpose of this open label study is to evaluate longer term tolerability and potential effectiveness of transcranial ultrasound in people with attention deficit hyperactive disorder (ADHD).

Detailed Description

The primary cortical regions thought to be implicated in ADHD include the prefrontal, orbitofrontal, and anterior cingulate cortices. A possible treatment approach for ADHD would employ a process desi...

Eligibility Criteria

Inclusion

  • Diagnosis of Attention Deficit Hyperactive Disorder (ADHD)
  • Failure to respond to traditional symptom management (e.g. stimulants, psychoeducation, cognitive-behavior therapy, etc.)
  • Score of at least 8 (4 ADHD-positive items) on the Adult ADHD Self-Report Questionnaire (ASRS-V1.1)
  • At least 18 years of age

Exclusion

  • • Subjects unable to give informed consent
  • Subjects who would not be able to lay down without excessive movement in a calm environment sufficiently long enough to be able to achieve sleep
  • Recent surgery or dental work within 3 months of the scheduled procedure.
  • Pregnancy, women who may become pregnant or are breastfeeding
  • Advanced terminal illness
  • Any active cancer or chemotherapy
  • Any other neoplastic illness or illness characterized by neovascularity
  • Macular degeneration
  • Subjects with scalp rash or open wounds on the scalp (for example from treatment of squamous cell cancer)
  • Advanced kidney, pulmonary, cardiac or liver failure

Key Trial Info

Start Date :

July 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 2 2026

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04497363

Start Date

July 1 2020

End Date

March 2 2026

Last Update

September 28 2022

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Neurological Associates of West LA

Santa Monica, California, United States, 90403

2

Neurological Associates of West Los Angele

Santa Monica, California, United States, 90403