Status:
ACTIVE_NOT_RECRUITING
Analysis of Coronavirus Disease 19 (COVID-19) Convalescent Plasma
Lead Sponsor:
City of Hope Medical Center
Collaborating Sponsors:
National Cancer Institute (NCI)
California Institute for Regenerative Medicine (CIRM)
Conditions:
Asymptomatic COVID-19 Infection Laboratory-Confirmed
Symptomatic COVID-19 Infection Laboratory-Confirmed
Eligibility:
All Genders
18+ years
Brief Summary
Plasma from patients who have recovered from coronavirus disease 2019 (COVID-19) is referred to as COVID-19 convalescent plasma (CCP), and may contain antibodies against SARS-CoV-2, the virus responsi...
Detailed Description
PRIMARY OBJECTIVES: I. Establish a testing service for screening prospective donors of coronavirus disease 2019 (COVID-19) convalescent plasma (CCP). II. Characterize the titer and neutralizing prop...
Eligibility Criteria
Inclusion
- For COVID-19 convalescent individuals:
- Age: ≥ 18 years
- Evidence of COVID-19 documented by a laboratory test either by: a diagnostic test (e.g., a NP swab) at the time of illness OR a positive serological test for SARS-CoV-2 antibodies after recovery, if prior diagnostic testing was not performed at the time COVID-19 was suspected.
- Note: If volunteers can't provide evidence of COVID-19, but are otherwise eligible, then we will test them for SARS-CoV-2 antibodies to confirm eligibility.
- Be willing to complete a pre-screening questionnaire
- Be willing to donate blood samples
- Permit medical record review
- For prospective CCP donors only: weigh more than 110 pounds and be in general good health
- For (COVID-19 convalescent plasma (CCP) recipients:
- Be enrolled in a clinical trial involving the infusion of CCP for the treatment of COVID-19.
- Be willing to provide blood samples
- Permit medical record review
Exclusion
Key Trial Info
Start Date :
July 13 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 13 2026
Estimated Enrollment :
95 Patients enrolled
Trial Details
Trial ID
NCT04497779
Start Date
July 13 2020
End Date
October 13 2026
Last Update
December 5 2025
Active Locations (1)
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1
City of Hope Medical Center
Duarte, California, United States, 91010