Status:

COMPLETED

Sweet Tooth: Nature or Nurture? Role of Long-term Dietary Sweetness Exposure on Sweetness Preferences

Lead Sponsor:

Wageningen University

Collaborating Sponsors:

Bournemouth University

TKI Agri & Food

Conditions:

Food Preferences

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

In recent years, social pressure has been exerted towards lowering sugar and sweetness levels in foods, with the aim of decreasing the sweetness preference of the general population. However, the resi...

Detailed Description

Evidence supporting sweetness preference alterations via variations in dietary sweetness exposure is limited. Most studies investigating this focused only on specific sweet elements in the diet, (e.g....

Eligibility Criteria

Inclusion

  • Good general health;
  • Age 18 - 65 years;
  • Body mass index 18.5 - 30 kg/m2;
  • Having normal taste ability (assessed with taste strips test);
  • Having normal glucose levels in blood (assessed with a finger prick);
  • Able to provide informed consent;
  • Able to attend Wageningen University, as required for testing.

Exclusion

  • Diagnosed with diabetes currently or in the past;
  • Has been notified to have insulin resistance currently or in the past;
  • Diagnosed with endocrine diseases or other metabolic diseases that influence metabolism;
  • Diagnosed with eating disorders;
  • Diagnosed with taste or smell disorder;
  • Pregnant or lactating during the study intervention;
  • Gain or loss of more than 3 kg in the last three months prior to study entry;
  • Suffering from lack of appetite (self-report);
  • Use of medication that may influence study results; such as medication that may affect blood sugar;
  • Having a food allergy or/and food intolerance for foods used in the preference testing (e.g. lactose intolerance, celiac disease, egg allergy);
  • Consumes more than 14 glasses of alcohol per week;
  • Use of soft or hard drugs (e.g. cannabis);
  • Student or personnel of Nutrition and Health at Wageningen University;
  • Participating in another study/studies or planning to participate in another study.
  • Specific criteria for withdrawal:
  • Pregnancy;
  • Weight change of 4 kg or more. In a case of systematic weight change - a subject has gained or lost 4 kg or more at the 3-month period, he/she will be excluded from the study (stop criterion).

Key Trial Info

Start Date :

October 20 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 5 2024

Estimated Enrollment :

180 Patients enrolled

Trial Details

Trial ID

NCT04497974

Start Date

October 20 2020

End Date

June 5 2024

Last Update

June 13 2024

Active Locations (1)

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Department of Human Nutrition, Wageningen University

Wageningen, Netherlands