Status:

COMPLETED

Evaluation of the Retinal Health Monitoring System Thickness Module

Lead Sponsor:

Kubota Vision Inc.

Conditions:

Macular Edema

Macular Degeneration

Eligibility:

All Genders

50+ years

Brief Summary

Evaluate the ability and accuracy of the Retinal Health Monitoring System - Retinal Thickness Module (RHMS - RTM).

Detailed Description

Evaluation of the Retinal Health Monitoring System - Retinal Thickness Module in subjects with normal macular thickness and subjects with center-involving macular edema.

Eligibility Criteria

Inclusion

  • Age ≥50.
  • Corrected visual acuity (VA) of 20/125 or better, in the study eye(s)
  • Media clarity, undilated pupil size, and subject cooperation sufficient to obtain adequate OCT B-scans in the study eye(s)
  • Able to perform self-testing of retinal thickness with the RHMS-RTM after training
  • Able and willing to provide written informed consent before undergoing any study-related procedures
  • Group 1: Macula with normal thickness \[central subfield thickness (CST): \<305μm in women, and \<320μm in men as measured by Heidelberg Spectralis SD-OCT in at least one eye. Patients diagnosed with dry AMD are eligible for enrollment into Group 1. No history of wAMD, DR, or RVO in either eye
  • Group 2 and Group 3, in at least one and the same eye: History of center-involving macular edema due to wAMD (Group 2); or DR or RVO (Group 3); Macular edema on SD-OCT with CST ≥305 μm in women, and ≥320μm in men as measured by Heidelberg Spectralis SD-OCT.

Exclusion

  • History of corneal refractive surgery \[e.g., laser-assisted in situ keratomileusis (LASIK), photorefractive keratectomy (PRK), radial keratotomy (RK)\] in the study eye(s)
  • History of epiretinal membrane, vitreomacular traction, or macular hole in the study eye(s)
  • Participation in any study using an investigational drug within 30 days of screening or an investigational device within 60 days of screening
  • Refractive error within defined limits
  • History of photocoagulation laser scar or other retinal scar in the central 3 mm of the macula, in the study eye(s)

Key Trial Info

Start Date :

November 11 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 25 2021

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT04499703

Start Date

November 11 2020

End Date

January 25 2021

Last Update

February 18 2021

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Inselspital, University Hospital Bern, Department of Ophthalmology

Bern, Switzerland, 3010