Status:
ENROLLING_BY_INVITATION
Neuronal Mechanisms of Human Episodic Memory
Lead Sponsor:
Cedars-Sinai Medical Center
Collaborating Sponsors:
Johns Hopkins University
University of Colorado, Denver
Conditions:
Epilepsy Intractable
Eligibility:
All Genders
13+ years
Phase:
NA
Brief Summary
The purpose the research is to better understand how the human brain accomplishes the basic cognitive tasks of learning new information, recalling stored information, and making decisions or choices a...
Detailed Description
The rapid formation of new memories and the recall of old memories to inform decisions is essential for human cognition, but the underlying neural mechanisms remain poorly understood. The long-term go...
Eligibility Criteria
Inclusion
- Intractable epilepsy, undergoing invasive monitoring
- Age ≥13
- Full Scale Intelligence Quotient \> 70
- Ability to comprehend and perform simple behavioral tasks by pressing buttons on laptop computer in response to questions.
Exclusion
- Determination by clinicians and investigators that a patient is unable to complete the behavioral tasks required for the protocol due to either cognitive limits, psychological limits, or pain.
Key Trial Info
Start Date :
August 12 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 31 2026
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04500119
Start Date
August 12 2020
End Date
July 31 2026
Last Update
December 26 2025
Active Locations (1)
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1
Cedars-Sinai Medical Center
Los Angeles, California, United States, 90048