Status:

COMPLETED

Prospective Multicenter Observational Study of Atezolizumab Combination Therapy in Lung Cancer (J-TAIL-2)

Lead Sponsor:

Chugai Pharmaceutical

Collaborating Sponsors:

Japan Lung Cancer Society

Conditions:

Non-small Cell Lung Cancer

Extensive Disease Small Cell Lung Cancer

Eligibility:

All Genders

20+ years

Brief Summary

This is a multi-center observational study of atezolizumab combination therapy in patients with unresectable, advanced and recurrent non-small cell lung cancer(NSCLC) or extensive disease small cell l...

Detailed Description

Primary endpoint: 12 months OS, Secondary endpoints: Overall Survival(OS), 6 months survival rate(6mo OS), 12 months survival rate(12mo OS), Progression-Free Survival(PFS), Time to treatment failure (...

Eligibility Criteria

Inclusion

  • \< non-small cell lung cancer cohort\>
  • Patients 20 years of age or older at the time of signed consent.
  • Patients with unresectable, advanced and recurrent non-small cell lung cancer.
  • Patients who are scheduled to start atezolizumab combination therapy in clinical practice, based on the atezolizumab package insert and the Optimal Use Promotion Guideline.
  • Patients who signed informed consent form before enrolling the study. The consent from a legally acceptable representative is required for the patients with uncertain capacity of judgments.
  • \<extensive disease small cell lung cancer cohort\>
  • Patients 20 years of age or older at the time of signed consent.
  • Patients with extensive disease small cell lung cancer.
  • Patients who are scheduled to start atezolizumab combination therapy in clinical practice, based on the atezolizumab package insert and the Optimal Use Promotion Guideline.
  • Patients who signed informed consent form before enrolling the study. The consent from a legally acceptable representative is required for the patients with uncertain capacity of judgments.

Exclusion

  • \< non-small cell lung cancer cohort\> (1) Patients who are unsuitable for enrolment into the study by the investigator's judgment.
  • \<extensive disease small cell lung cancer cohort\>
  • (1) Patients who are unsuitable for enrolment into the study by the investigator's judgment.

Key Trial Info

Start Date :

August 21 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

February 3 2023

Estimated Enrollment :

1221 Patients enrolled

Trial Details

Trial ID

NCT04501497

Start Date

August 21 2020

End Date

February 3 2023

Last Update

April 2 2024

Active Locations (148)

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Page 1 of 37 (148 locations)

1

Akashi Medical Center

Akashi, Japan

2

Hyogo Cancer Center

Akashi, Japan

3

Hyogo Prefectural Amagasaki General Medical Center

Amagasaki, Japan

4

Asahikawa Medical University Hospital

Asahikawa, Japan

Prospective Multicenter Observational Study of Atezolizumab Combination Therapy in Lung Cancer (J-TAIL-2) | DecenTrialz