Status:

UNKNOWN

Dysautonomic Phenotype in Male Patients With MECP2 Mutation

Lead Sponsor:

University Hospital, Brest

Conditions:

MECP2-Related Severe Neonatal Encephalopathy

Dysautonomia

Eligibility:

MALE

Up to 16 years

Brief Summary

Dysautonomic signs are well known among girls with a Rett Syndrom. Rett syndrom is caused by a MECP2 mutation in 95% of cases. We want to search dysautonomic signs among boys with a MECP2 mutations be...

Detailed Description

First, we will launch a national call for participation in all the genetics departments in France to research boys with a missense or a non-sens mutation in the MECP2 gene. Our inclusion criteria is :...

Eligibility Criteria

Inclusion

  • less than 16 years old or dead before 16 years old patients of masculin sex with a missense or non-sens mutation in the MECP2 gene -

Exclusion

  • patient under judicial protection or participation refusal by one of the legal guardian
  • \-

Key Trial Info

Start Date :

August 15 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 13 2021

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT04502199

Start Date

August 15 2020

End Date

January 13 2021

Last Update

August 6 2020

Active Locations (7)

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Page 1 of 2 (7 locations)

1

CHU de Besançon

Besançon, France

2

CHRU de Brest

Brest, France, 29609

3

CHRU de Lille

Lille, France

4

Hospices Civiles de Lyon

Lyon, France