Status:

COMPLETED

LDN and tDCS in Fibromyalgia

Lead Sponsor:

Centro Universitario La Salle

Collaborating Sponsors:

Hospital de Clinicas de Porto Alegre

Conditions:

Fibromyalgia

Eligibility:

FEMALE

8-65 years

Phase:

PHASE2

PHASE3

Brief Summary

Fibromyalgia is a complex generalized and diffuse musculoskeletal chronic pain; and pharmacological approaches are widely used to relieve pain and increase life quality. In this context, low-dose nalt...

Eligibility Criteria

Inclusion

  • signed the consent form
  • women from 18 to 65 years
  • confirmed diagnosis of fibromyalgia according 2016 American College of Rheumatology criteria
  • read and write
  • pain higher than 6 in the Visual Analogue Scale (VAS), in the last 3 months
  • chronic stable treatment in the last 3 months.

Exclusion

  • in use of opioid drugs;
  • pregnancy or not using anticontraceptive
  • history of alcohol or drug abuse in the last 6 months
  • history of neurological pathologies
  • history of arrhythmia
  • history of use of drugs that might change vascular response
  • history of head trauma
  • history of neurosurgery
  • decompensated systemic diseases or chronic inflammatory diseases (lupus, rheumatoid arthritis, Sjogren syndrome, Reiter syndrome)
  • history of non-compensated hypothyroidism
  • personal history of cancer.

Key Trial Info

Start Date :

August 1 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2020

Estimated Enrollment :

92 Patients enrolled

Trial Details

Trial ID

NCT04502251

Start Date

August 1 2018

End Date

July 1 2020

Last Update

August 6 2020

Active Locations (1)

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Universidade La Salle

Canoas, Rio Grande do Sul, Brazil, 92010-000