Status:
UNKNOWN
18F-FDG and 68Ga-FAPI PET/CT in Crohn's Disease
Lead Sponsor:
Peking Union Medical College Hospital
Conditions:
Crohn Disease
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
Intestinal stricture is a complication of Crohn's disease (CD), which is thought to be the result of chronic transmural inflammation combined with a dysregulated wound-healing process. While inflammat...
Detailed Description
Patients with intestinal stricture will undergo 18F-FDG and 68Ga-FAPI PET/CT on two consectutive days. The accumulation of 18F-FDG and 68Ga-FAPI at the site of stricture will be determined by standard...
Eligibility Criteria
Inclusion
- Written informed consent signed
- Crohn's disease patients with proofs of intestine stricture by other modalities, e.g. MRI, CT, ultrasound, and/or endoscopy.
Exclusion
- Known hypersensitivity to any of the excipients of 18F-FDG and 68Ga-FAPI.
- If the patients are on metformin, discontinuation of 48 hours is required before 18F-FDG injection to minimize the bowel uptake.
- Pregnant or breast-feeding women.
- Any mental condition rendering the patient unable to understand the nature, scope, and possible consequences of the study, and/or evidence of an uncooperative attitude.
Key Trial Info
Start Date :
September 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2021
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04502303
Start Date
September 1 2020
End Date
September 1 2021
Last Update
August 7 2020
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.