Status:
UNKNOWN
Heterogeneity of Critical Illness: a Cohort Study
Lead Sponsor:
University Medical Center Groningen
Conditions:
Critically Ill
Organ Failure, Multiple
Eligibility:
All Genders
18+ years
Brief Summary
Rationale: There is large heterogeneity in disease states of critically ill patients at ICU admittance and there is also large heterogeneity in their disease severity during ICU stay. Still, some pati...
Detailed Description
Nature and extent of the burden and risks associated with participation, benefit and group relatedness: \<All patients will undergo physical examination, including ultrasound evaluation upon ICU admis...
Eligibility Criteria
Inclusion
- Adults Definition: age ≥18 years.
- Emergency admission to the ICU Definition: patients who are acutely admitted to the ICU due to acute or unexpected critical illness, either from the emergency department or the ward or transferred from an ICU (or a ward) from another hospital.
Exclusion
- Planned admission
- Absence of an invasive arterial or venous line for blood sampling.
- Any continued cardiopulmonary resuscitation efforts upon admission which limit access to the patient for research activities.
- Main ICU admission reason chronic (non-invasive) home ventilation
- Main ICU admission reason normothermic treatment after cardiac arrest
- Main ICU admission reason ischemic stroke, intracerebral bleeding, or isolated neurotrauma
- Main ICU admission reason Coronavirus Disease 2019 (COVID-19)
- Solid organ or hematopoietic stem cell transplant during current hospital admission
- Strict isolation due to any contagious disease
- No informed consent
Key Trial Info
Start Date :
October 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2023
Estimated Enrollment :
2000 Patients enrolled
Trial Details
Trial ID
NCT04502511
Start Date
October 1 2020
End Date
December 1 2023
Last Update
August 6 2020
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