Status:

COMPLETED

Control-IQ Observational (CLIO) Post-Approval Study

Lead Sponsor:

Tandem Diabetes Care, Inc.

Collaborating Sponsors:

University of California, San Diego

Conditions:

Diabetes Mellitus, Type 1

Eligibility:

All Genders

6+ years

Brief Summary

Post-approval 522 study designed to collect primarily safety data on the US FDA-cleared product, t:slim X2 insulin pump with Control-IQ technology (Control-IQ system).

Detailed Description

Post-approval study designed to collect primarily safety data on the US FDA-cleared product, t:slim X2 insulin pump with Control-IQ technology (Control-IQ system), by assessing the rate of severe hypo...

Eligibility Criteria

Inclusion

  • Patients with self-reported type 1 diabetes who have been prescribed the Control-IQ system.
  • At least 6 years of age
  • Using Humalog or Novolog insulin
  • For females, not pregnant or planning pregnancy in the next 12 months.
  • Agreement to use the t:slim X2 with Control-IQ technology, and to continue use for at least 12 consecutive months after study enrollment.
  • Agree to provide HbA1c result, obtained within the 6-month period prior to enrollment.
  • Ability to respond to alerts and alarms, and to provide basic diabetes self-management.
  • Patients who reside full-time in the United States.
  • Willingness to download the t:connect Mobile application to their Smartphone and keep it active throughout the study. Patients unable to use t:connect Mobile application must be willing to manually upload their insulin pump data to t:connect every three months and at the completion of the study.
  • Subject has read, understood and agreed to participate in the study, and has electronically signed the Informed Consent Form (ICF).

Exclusion

  • Self-reported type 2 diabetes
  • \< 6 years of age
  • Use of any glucose-lowering therapy other than Humalog or Novolog insulin
  • Inability to respond to alerts and alarms, or to provide basic diabetes self-management.
  • Pregnancy
  • Subjects who have not signed the ICF.

Key Trial Info

Start Date :

August 4 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 26 2023

Estimated Enrollment :

3157 Patients enrolled

Trial Details

Trial ID

NCT04503174

Start Date

August 4 2020

End Date

June 26 2023

Last Update

December 8 2023

Active Locations (1)

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1

Tandem Diabetes

San Diego, California, United States, 92121