Status:
COMPLETED
CLoWI Versus PCA Morphine for Pain Control After Major Abdominal Surgery
Lead Sponsor:
JurongHealth
Conditions:
Surgical Wound
Post-Op Complication
Eligibility:
All Genders
21-80 years
Phase:
NA
Brief Summary
Major abdominal surgery is associated with significant complications which may lead to morbidity and mortality. Pain experienced after surgery affects the recovery from surgery. Our study aims to eva...
Detailed Description
Major intra-abdominal surgery represents one of the commonest groups of surgical procedures performed both worldwide and within Singapore. Common general surgical conditions requiring major intra-abdo...
Eligibility Criteria
Inclusion
- Planned for elective or urgent# open abdominal surgery
- Abdominal Surgery may include the following procedures:
- A) Urgent laparotomy for perforated viscus, intestinal obstruction. B) Elective abdominal surgery for upper and lower gastrointestinal surgery
- Ability to provide informed consent. A signed and dated written informed consent prior to study participation.
- Age 21 to 80 years for both males and females
Exclusion
- Female subject who is pregnant
- Inability to comply with PCA instructions due to physical disabilities. For example, visual or hearing impairment, arthritis, peripheral neuropathy.
- Known allergy to local anaesthetic or opioid drugs (Morphine).
- Current or recent on opioid therapy. For example due to chronic pain illness, opioid (or other) drug abuse or recent surgery.
- Severe comorbid diseases including liver cirrhosis, renal failure requiring dialysis, Grade 4 NYHA (New Yoke Heart Association) heart failure, respiratory illness requiring NIV (Non-Invasive Ventilation), etc.
- Severe associated acute illness American Society of Anesthesiologists (ASA) Grade 4 or 5 where survival following surgery is not expected
Key Trial Info
Start Date :
December 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2022
Estimated Enrollment :
52 Patients enrolled
Trial Details
Trial ID
NCT04503720
Start Date
December 1 2017
End Date
June 30 2022
Last Update
July 12 2024
Active Locations (2)
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1
National University Hospital
Singapore, Singapore, 119074
2
Ng Teng Fong General Hospital
Singapore, Singapore, 609606