Status:

COMPLETED

Invasive Left Heart Catheterization Registry

Lead Sponsor:

Samsung Medical Center

Conditions:

Heart Failure With Preserved Ejection Fraction

Left Ventricular Diastolic Dysfunction

Eligibility:

All Genders

19+ years

Brief Summary

Retrospectively enrolled suspicious of heart failure with preserved ejection fraction (HFpEF) patients who underwent left heart catheterization with the measurement of left ventricular end-diastolic p...

Detailed Description

Heart failure (HF) with preserved ejection fraction (HFpEF) remains a poorly understood clinical syndrome without effective targeted therapies. The clinical syndrome of HFpEF develops from a complex i...

Eligibility Criteria

Inclusion

  • Left ventricular ejection fraction \> 50%
  • Patients who had a symptom and/or signs of heart failure (dyspnea on exertion, chest discomfort, fatigue, dizziness, or ankle edema)
  • Patients who underwent left heart catheterization with the measurement of left ventricular end-diastolic pressure

Exclusion

  • Left ventricular ejection fraction \<50%
  • Acute coronary syndrome
  • More than moderate valvular heart disease
  • Primary cardiomyopathies such as dilated cardiomyopathy and hypertrophic cardiomyopathy, amyloidosis
  • Pulmonary arterial hypertension
  • Heart transplantation
  • Constrictive pericarditis
  • Stress-induced cardiomyopathy

Key Trial Info

Start Date :

December 13 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 31 2021

Estimated Enrollment :

404 Patients enrolled

Trial Details

Trial ID

NCT04505449

Start Date

December 13 2019

End Date

March 31 2021

Last Update

October 27 2022

Active Locations (1)

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1

Samsung Medical Center

Seoul, South Korea, 06351