Status:
COMPLETED
Follow-up of Respiratory Sequelae of Hospitalized Patients With COVID-19
Lead Sponsor:
Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
Conditions:
Covid19
Dyspnea
Eligibility:
All Genders
18+ years
Brief Summary
The objective of this multicenter observational study is to describe respiratory sequelae of COVID-19 patients hospitalized for severe pneumonia requiring oxygen supply.
Detailed Description
Main objective To assess respiratory sequelae after SARS-CoV-2 infection in hospitalized patients with severe pneumonia requiring oxygen supply and followed up for 6 months after hospital discharge (s...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Age ≥ 18 years old
- SARS-CoV-2 infection proven by RT-PCR and/or retrospective serology and/or a COVID-19 syndrome with evocative chest CT scan
- Hospitalized for severe pneumonia due to SARS-CoV-2 infection requiring oxygen supply
- Exclusion criteria:
- Not hospitalized for a severe COVID-19 infection
- Absence of respiratory symptoms at V1 (3 months after hospital discharge), defined as: absence of residual exertional dyspnea and persistent pulmonary infiltrates on follow-up chest radiography at 1 month (if available), transcutaneous oxyhemoglobin saturation \>94% and normal pulmonary auscultation
- Patient with pre-existing chronic lung disease prior to the first episode of COVID-19: chronic obstructive pulmonary disease confirmed by respiratory function testing with a forced expiratory volume in one second (FEV1) \< 50% and/or a diffusing capacity for carbon monoxide (DLCO) \< 60%, fibrotic lung disease or chronic respiratory failure (on long-term oxygen therapy)
- Opposition to participation in the study
- Patient under legal protection
- Patient not affiliated to/beneficiary of a social security scheme
Exclusion
Key Trial Info
Start Date :
June 10 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 15 2021
Estimated Enrollment :
332 Patients enrolled
Trial Details
Trial ID
NCT04505631
Start Date
June 10 2020
End Date
January 15 2021
Last Update
November 17 2025
Active Locations (14)
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1
Groupe Hospitalier de Mulhouse et de la Région Sud-Alsace
Mulhouse, Alsace, France, 68100
2
Centre Hospitalier de la Côte Basque - Bayonne
Bayonne, France
3
Centre Hospitalier Métropole Savoie
Chambéry, France
4
Centre Hospitalier Colmar
Colmar, France