Status:
COMPLETED
Tryptophan Supplementation to Improve Night Shift Workers' Health
Lead Sponsor:
National Yang Ming Chiao Tung University
Conditions:
Sleep
Mood
Eligibility:
All Genders
20+ years
Phase:
NA
Brief Summary
This randomized cross-over double-blinded trial aims to investigate the health effect of oral l-tryptophan supplementation on workers who rotate night shift work, and to examine the influences of diff...
Detailed Description
This study aims to investigate the health effect of oral l-tryptophan supplementation on workers who rotate night shift work, and to examine the influences of different frequencies and timings of supp...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Age: adults \>=20 y/o
- Adults who had night shift schedule \>1 month before enrollment, and will have similar night shift schedule in the following 2 months. (Eligible night shift schedule: \>1 day of evening or night shift in a week)
- People who will not have plans to travel to another time zone in the following 2-3 months
- People who will plan to stay in the same job position for the following 3 months
- People who have no experience in taking tryptophan or melatonin supplement in the past month
- Body weight \>= 50kg and \<=80kg
- Non-pregnant, non-breastfeeding, not taking contraceptives
- Not under treatment of steroids, not taking sleeping pills
- Exclusion criteria:
- diagnosis of renal or liver diseases
- diagnosis of Cushing's Disease, Addison's disease
- psychiatric diagnosis, such as depression and anxiety disorders
- neurological diseases such as dementia, epilepsy, Parkinson's disease
Exclusion
Key Trial Info
Start Date :
September 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2020
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04505800
Start Date
September 1 2019
End Date
December 31 2020
Last Update
March 22 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
National Yang-Ming University
Taipei, Taiwan, 112