Status:
COMPLETED
Quantitation of Glymphatic Functioning in Sleep and Meditative States
Lead Sponsor:
Vanderbilt University Medical Center
Conditions:
Parkinson Disease
Sleep
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
This involves development and application of magnetic resonance imaging (MRI) methods for visualizing hemodynamic and metabolic relationships in healthy volunteers with advanced meditation experience.
Detailed Description
This study is evaluating the glymphatic system during awake, sleep, and meditative states.
Eligibility Criteria
Inclusion
- Ages 14-45
- "Adept meditator status"
Exclusion
- Any non-MR compatible material implant, or contraindication to MR scanning
- Claustrophobia or inability to lie still for prolonged periods of time
- Participants with a recent (less than 2 months) infection, tattoo, or wound
- No consumption of stimulants or alcohol within 12 hours of the study visit
- clinical diagnosis of any major neurological or psychological condition
- Taking benzodiazepines, cholinestorase inhibitors, anti-psychotics, opioids, MAO inhibitors
Key Trial Info
Start Date :
February 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2024
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT04506892
Start Date
February 1 2021
End Date
December 1 2024
Last Update
August 6 2025
Active Locations (1)
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1
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37212-3160