Status:

COMPLETED

Fasting for Brain and Heart Health (FBHH)

Lead Sponsor:

TrueNorth Health Foundation

Conditions:

Insulin Resistance

Eligibility:

All Genders

40-70 years

Brief Summary

This pilot study is designed to investigate the effect of water-only fasting and refeeding on the homeostatic model of insulin resistance (HOMA-IR), a measure of insulin resistance.

Detailed Description

Ischemic stroke is a leading cause of death and a major public health burden. Data suggests that insulin resistance is a potential risk factor for cardiovascular disease, including ischemic stroke, an...

Eligibility Criteria

Inclusion

  • Any gender
  • 40-70 years old
  • Fasting plasma glucose \<12 6mg/dL and/or hemoglobin A1c \<7%
  • Body Mass Index (BMI) \>25 kg/m2
  • Elect and qualify for a water-only fast of at least 10 consecutive days
  • Provide informed consent

Exclusion

  • Active malignancy
  • Active inflammatory disorder including classic autoimmune connective tissue (Lupus, Sjogrens, ANCA), multiple sclerosis, and inflammatory bowel disorders (Ulcerative colitis, Crohn's)
  • Stroke or heart attack within the last 90 days

Key Trial Info

Start Date :

April 2 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

February 10 2020

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT04507516

Start Date

April 2 2019

End Date

February 10 2020

Last Update

August 11 2020

Active Locations (1)

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TrueNorth Health Center

Santa Rosa, California, United States, 95404