Status:

RECRUITING

Pharmacist Guided Pre-emptive Pharmacogenetic Testing in Antidepressant Therapy

Lead Sponsor:

PD Dr. med. Thorsten Mikoteit

Collaborating Sponsors:

Psychiatrische Dienste Solothurn

Privatklinik Wyss

Conditions:

Depression

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

In this study at the Solothurn Psychiatric Clinic, the investigators compare the effectiveness and tolerability of antidepressant pharmacotherapy in three groups. In the intervention group, the physic...

Eligibility Criteria

Inclusion

  • ≥ 18 years old
  • Diagnosis unipolar moderate or severe depressive episode or recurrent depressive disorder (ICD10: F32.1/32.2/33.1/33.2)
  • HAM-D17 ≥ 17

Exclusion

  • Acute suicide risk
  • Psychotic symptomatology
  • Other acute serious psychiatric disorder other than depression
  • Excessive consumption of alcohol and/or drugs
  • Severe acute - or severe chronic somatic diseases
  • Pregnant / lactating women
  • Under current treatment with fluoxetine

Key Trial Info

Start Date :

September 15 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2025

Estimated Enrollment :

190 Patients enrolled

Trial Details

Trial ID

NCT04507555

Start Date

September 15 2020

End Date

December 31 2025

Last Update

January 20 2025

Active Locations (4)

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Page 1 of 1 (4 locations)

1

Privatklinik Wyss

Münchenbuchsee, Canton of Bern, Switzerland, 3053

2

Psychiatrische Dienste Solothurn

Solothurn, Canton of Solothurn, Switzerland, 4503

3

Luzerner Psychiatrie AG

Sankt Urban, Switzerland, 4915

4

Psychiatrische Universitätsklinik Zürich

Zurich, Switzerland, 8032