Status:
RECRUITING
Skeletal Health and Bone Marrow Composition in Newly Diagnosed Adolescents With Crohn Disease
Lead Sponsor:
Massachusetts General Hospital
Conditions:
Inflammatory Bowel Disease
Crohn Disease
Eligibility:
All Genders
13-20 years
Brief Summary
The investigators will be evaluating bone marrow composition via magnetic resonance imaging in newly diagnosed adolescents with Crohn disease (CD) compared to healthy, matched controls. The investigat...
Detailed Description
Less than optimal bone health has been seen in children that have inflammatory bowel disease (IBD), including Crohn disease (CD). This can present as low bone density or altered bone structure, weaken...
Eligibility Criteria
Inclusion
- Crohn's Disease diagnosed within the past 3 months, or a healthy, matched control
Exclusion
- Participants with chronic disease known to affect skeletal metabolism
- Participants on certain medications within the prior 3 months that are known to affect skeletal metabolism
- Participants who are pregnant
- Participants who have a history of: claustrophobia, internal body metal that is not compatible with MRI machine, or a known abnormality on or adjacent to the left knee
Key Trial Info
Start Date :
September 10 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
92 Patients enrolled
Trial Details
Trial ID
NCT04508088
Start Date
September 10 2020
End Date
December 1 2026
Last Update
October 30 2025
Active Locations (1)
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1
Boston Children's Hospital
Boston, Massachusetts, United States, 02115