Status:
COMPLETED
Scintigraphic Evaluation of Contractile and Coronary Reserve in Patients With Ischemic Cardiomyopathy
Lead Sponsor:
Tomsk National Research Medical Center of the Russian Academy of Sciences
Conditions:
Ischemic Cardiomyopathy
Eligibility:
All Genders
18-70 years
Brief Summary
According to single-photon emission computed tomography, the left ventricular contractile and coronary flow reserve (CFR) will be assessed in patients with ischemic cardiomyopathy. According to these ...
Detailed Description
Before surgical intervention, all patients pass routine clinical analyzes undergo coronary angiography and 2D echocardiography. Some of patients in the ICM-1 and ICM-2 groups undergo stress echocardio...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- А) For ICM group:
- History of myocardial infarction (MI) or revascularization (CABG or PCI);
- \> 75% stenosis of left main or proximal LAD and/ or stenosis of \> 75% of ≥2 epicardial vessels (based on coronary angiography (CA) data);
- LV EF \<40% and increase in LV volumes according to echocardiography (ECHO)
- B) For GBPS Control group
- Absence of obstructive coronary artery lesion;
- Absence of history of MI and revascularization.
- C) For CFR Control group
- Presence of obstructive coronary artery lesion;
- Indications for coronary artery bypass grafting;
- Exclusion Criteria (for all groups):
- Presence of contraindications to the stress test with inotropic stimulation;
- Inflammatory myocardial diseases;
- The presence of severe hematological, neurological disorders, other psychosomatic conditions that impede research;
- Life expectancy of less than 6 months (acute renal and hepatic failure, mental illness, malignant neoplasms of the final stages, unsuitable correction of brain injury).
Exclusion
Key Trial Info
Start Date :
September 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2021
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT04508608
Start Date
September 1 2018
End Date
September 1 2021
Last Update
October 6 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Cardiology Research Institute, Tomsk National Research Medical Centre, Russian Academy of Sciences
Tomsk, Russia, 634000