Status:

COMPLETED

A Study Using Electronic Health Information to Learn About Rivaroxaban Compared to Warfarin in Participants With Non-valvular Atrial Fibrillation (NVAF) and Diabetes

Lead Sponsor:

Bayer

Collaborating Sponsors:

Janssen Research & Development, LLC

Conditions:

Atrial Fibrillation

Eligibility:

All Genders

18+ years

Brief Summary

In people with type 2 diabetes, the body does not make enough of a hormone called insulin or does not use insulin well. This results in high blood sugar levels. People with diabetes are more likely t...

Eligibility Criteria

Inclusion

  • Be ≥18 years of age at the time of anticoagulation initiation
  • Have diagnoses of type 2 diabetes and Non-valvular atrial fibrillation (NVAF)
  • Have no record of prior oral anticoagulant (OAC) use in the prior 12-months
  • Newly initiated on Rivaroxaban or Warfarin (index date)
  • Have ≥12-months of electronic health record (EHR) activity prior to the index date and received care documented in the EHR database from at least one provider in the 12-months prior

Exclusion

  • Evidence of valvular heart disease defined as any rheumatic heart disease, mitral stenosis or mitral valve repair/replacement
  • Pregnancy
  • Use of rivaroxaban doses other than 15 mg once daily or 20 mg once daily or the presence of other indication(s) for OAC use
  • Any prior OAC utilization per written prescription or self-report at baseline

Key Trial Info

Start Date :

August 21 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 31 2021

Estimated Enrollment :

116049 Patients enrolled

Trial Details

Trial ID

NCT04509193

Start Date

August 21 2020

End Date

July 31 2021

Last Update

June 15 2022

Active Locations (1)

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US Optum De-Identified EHR data

Whippany, New Jersey, United States, 07981