Status:

COMPLETED

A Prospective & Retrospective Study on Ectopic Lymphoid-like Structures in Chronic Skins of Autoimmune Bullous Diseases

Lead Sponsor:

Gangnam Severance Hospital

Conditions:

Autoimmune Bullous Disease

Eligibility:

All Genders

19+ years

Phase:

NA

Brief Summary

The purpose of this study is to identify the presence or absence of ectopic lymph node-like structures in skin lesions of patients with autoimmune bullous disease and the subtypes of the cells deposit...

Eligibility Criteria

Inclusion

  • \<Presence of Ectopic Lymphoid-like Structures in the Skin lesion of Autoimmune Bullous Disease Patients\>
  • Prospective study
  • Adults over 19
  • Patietns who voluntarily signed the consent form
  • Patients who are diagnosed with autoimmune bullous disease through clinical, histological and serological tests
  • Retrospective study
  • Samples in human-derived banks from March 2013 to October 2018
  • Patients who are diagnosed with autoimmune bullous disease through clinical, histological and serological tests
  • Adults over 19 \<Treatment of Ectopic Lymphoid-like Structures in the Skin lesion of Autoimmune Bullous Disease Patients\>
  • Prospective study
  • Adults over 19
  • Patients who voluntarily signed the consent form
  • Patients who have skin lesions harboring ectopic lymph node-like structure in a prospective or retrospective manner
  • Patients who have chronic lesions sustained for more than 4 months during the treatment of systemic corticosteroids
  • Retrospective study
  • Patients who have skin lesions harboring ectopic lymph node-like structure in a retrospective manner
  • Paitents who have been treated for intralesional steroid injection
  • Patients who have data of photography to compare the clinical effects before and after intralesional corticosteroid treatment.

Exclusion

  • 1\. Patients who do not meet the criteria for autoimmune bullous disease

Key Trial Info

Start Date :

February 8 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 31 2022

Estimated Enrollment :

41 Patients enrolled

Trial Details

Trial ID

NCT04509570

Start Date

February 8 2019

End Date

October 31 2022

Last Update

July 19 2024

Active Locations (1)

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1

GangnamSeverance Hospital

Seoul, South Korea