Status:

COMPLETED

Target Gene Sequencing for Advanced Stage, Relapsed or Refractory Natural Killer/T-cell Lymphoma

Lead Sponsor:

Chinese Academy of Medical Sciences

Conditions:

Lymphoid Neoplasm

Eligibility:

All Genders

Brief Summary

Although modern radiation techniques combined with chemotherapy has greatly improved the local control and long-term survivals for patients with early-stage NKTCL, relapse and systemic dissemination a...

Eligibility Criteria

Inclusion

  • Diagnosis of NKTCL with typical morphology and immunophenotype, according to the 2008 World Health Organization classification of lymphomas;
  • stage III/IV disease; or relapsed or refractory disease after at least one line prior teratment;
  • age ≥ 18 years;
  • ECOG performance status 0-2;
  • at least one measurable lesion;
  • adequate hematological, hepatic, and renal functions;
  • life expectancy of more than 3 months.

Exclusion

  • Previously untreated stage I/II disease;
  • with no adequate tumour tissue;
  • any coexisting medical problems of sufficient severity to prevent full compliance with the study protocol.

Key Trial Info

Start Date :

May 10 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 1 2020

Estimated Enrollment :

26 Patients enrolled

Trial Details

Trial ID

NCT04509804

Start Date

May 10 2018

End Date

January 1 2020

Last Update

August 12 2020

Active Locations (1)

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1

Mei Dong

Beijing, Beijing Municipality, China, 100021