Status:
UNKNOWN
Early Detection of CMP in Patients With Breast Cancer Using Cardiac Magnetic Resonance
Lead Sponsor:
RenJi Hospital
Collaborating Sponsors:
Ruijin Hospital
Shanghai Fifth People's Hospital
Conditions:
Breast Cancer
Chemotherapy Induced Systolic Dysfunction
Eligibility:
FEMALE
18-70 years
Brief Summary
Breast cancer is the most common cancers among women worldwide.Although chemotherapy and surgery have greatly improved the survival rate, most types of chemotherapy have been reported to have varying ...
Detailed Description
Breast cancer is the most common cancers among women worldwide. Although chemotherapy and surgery have greatly improved the survival rate, most types of chemotherapy have been reported to have varying...
Eligibility Criteria
Inclusion
- Age between 18-70 years old.
- Invasive breast cancer confirmed by Pathology
- Left ventricular ejection fraction ≥ 50%
- Having not received any prior systemic anti-cancer therapy for advanced disease
- an Eastern Cooperative Oncology Group（ECOG） performance status 0-1
- Providing written informed consent
- Inclusion Criteria for Control group:
- Absence of known systemic diseases
- Normal examinations
- Age between 18-70 years old.
- Providing written informed consent
Exclusion
- Age \<18 years old or \>70 years old
- Documented coronary artery disease or prior angiography for coronary artery disease (\>50% stenosis).
- Patients with bilateral invasive breast cancers.
- Patients with metastasis of breast cancer confirmed by imaging or pathology
- Patients with standard metallic contraindications to CMR or an estimated glomerular filtration rate \< 30 ml/min/1.73 m2.
Key Trial Info
Start Date :
October 30 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 1 2023
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT04510532
Start Date
October 30 2020
End Date
September 1 2023
Last Update
June 1 2023
Active Locations (1)
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1
Renji Hospital
Shanghai, Shanghai Municipality, China, 200127