Status:
RECRUITING
Tumor Molecular Profiling in Early Phase Clinical Trials
Lead Sponsor:
Oncology Institute of Southern Switzerland
Collaborating Sponsors:
Ente Ospedaliero Cantonale, Bellinzona
Istituto Cantonale di Patologia
Conditions:
Advanced Solid Tumor
Lymphoma
Eligibility:
All Genders
18+ years
Brief Summary
Prospective, single centre, non-interventional exploratory research project that will be conducted on biological material and health-related personal data collected.
Detailed Description
Single center, two-parts pilot, prospective study to assess the role of molecular tumor profiling in supporting patient enrollment in early phase clinical trials. Part A: patients with solid tumors o...
Eligibility Criteria
Inclusion
- Male or female patients age at least 18 years.
- Patients with histological diagnosis of advanced solid tumor or lymphoma who are potential candidates for early phase clinical trials.
- Eastern Cooperative Oncology Group (ECOG) Performance Status 0 or 1
- Live expectancy of at least 6 months.
- Availability of FFPE archival tumor tissue from previous surgery or diagnostic biopsy adequate for molecular analysis.
- Ability to understand the patient information and study consent. Signed and dated written informed consent must be available before performing any study-related procedure.
- Willing and able to comply with study procedures
Exclusion
- Presence of any clinical (e.g. concomitant disease, clinically significant symptoms, or non-clinical (psychological or social) conditions that would not make the patient eligible for enrolment in an early phase clinical trial.
- Any other active malignancy (other than the one for which the subject is being assessed for trial option) that is progressing or requiring active treatment with the exception of basal or squamous cell skin cancer, superficial bladder cancer, carcinoma in situ of any site.
Key Trial Info
Start Date :
October 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2026
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04510766
Start Date
October 1 2020
End Date
December 31 2026
Last Update
November 18 2025
Active Locations (1)
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1
Oncology Institute of Southern Switzerland
Bellinzona, Switzerland, 6500