Status:
UNKNOWN
Can Pan-Colonic Chromoendoscopy (PCC) Improve Adenoma Detection Rate in FIT-Positive-Patients: A Randomized Study
Lead Sponsor:
Singapore General Hospital
Conditions:
Colon Adenoma
Eligibility:
All Genders
50+ years
Phase:
NA
Brief Summary
Colonoscopy is the technique of choice for evaluation of patients with positive fecal occult blood (FIT). Identification of polyps and their removal has been shown to decrease colorectal cancer incide...
Detailed Description
Eligible subjects with positive screening FIT test referred to the Department of Gastroenterology, Singapore General Hospital will be approached and recruited. The included patients will be randomised...
Eligibility Criteria
Inclusion
- Age older than 50 years
- Positive stool FIT test or FOBT test
Exclusion
- Known inflammatory bowel disease
- Known polyposis syndromes
- Previous history of colon cancer and surgical resection
- Overt gastrointestinal bleeding
- Stool FIT or FOBT test performed during hospitalization
- Inadequate bowel preparation (Boston Bowel Preparation score \<6 or \<2 for each colonic segment)
- Poor patient tolerance to the procedure
- Pregnancy
- Concurrent intake of anticoagulants and thienopyridines (e.g., Clopidogrel), where these drugs cannot be suspended for the adequate duration before colonoscopy
- Patient with known history of hypersensitivity to Indigo carmine dye
Key Trial Info
Start Date :
July 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2022
Estimated Enrollment :
250 Patients enrolled
Trial Details
Trial ID
NCT04512612
Start Date
July 1 2020
End Date
August 1 2022
Last Update
August 13 2020
Active Locations (1)
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1
Singapore General Hospital
Singapore, Singapore, 169608