Status:
RECRUITING
The Contributions of Age Related Changes in the Sound Localization Pathway to Central Hearing Loss
Lead Sponsor:
University of Colorado, Denver
Collaborating Sponsors:
National Institutes of Health (NIH)
National Institute on Deafness and Other Communication Disorders (NIDCD)
Conditions:
Healthy Individuals
Hearing Loss, Central
Eligibility:
All Genders
40-89 years
Brief Summary
Age-related hearing loss, presbycusis, affects up to 50% of American adults. There are two main causes for presbycusis: 1) Progressive death of hair cells in the inner ear, and 2) Central hearing loss...
Eligibility Criteria
Inclusion
- Subjects age ranges
- a. 21 years (inclusive) and 89years (inclusive)
- Subjects exhibiting no poorer than a mild hearing loss, defined as hearing thresholds no worse than 40dBHL at any test frequency 250-4000 Hz based on pure tone audiometry
- Subjects scoring 26 or higher on a screening measure of cognitive status (Montreal Cognitive Screening Assessment; MoCA)
Exclusion
- Patients outside the age range of 21-89
- Patients with an air-bone gap greater than 10dBHL at any frequency
- Patients who are decisionally challenged and/or unable to complete speech perception testing. These patients are excluded based on the study requiring behavioral responses to some tests
- Patients with little command of the English language who are unable to understand and repeat back simple everyday English sentences.
- Illiterate patients
- Patients with neurodegenerative diseases.
Key Trial Info
Start Date :
October 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 29 2026
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04513782
Start Date
October 1 2020
End Date
May 29 2026
Last Update
August 15 2023
Active Locations (1)
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1
University of Colorado School of Medicine
Aurora, Colorado, United States, 80045