Status:
COMPLETED
Efficacy of a Multi-faceted Intervention Combining an Educational Outreach Visit to General Practitioners and Patient Education Material to Deprescribe Proton Pump Inhibitors (PPI): a Population-based, Pragmatic, Cluster-randomized Controlled Trial
Lead Sponsor:
Nantes University Hospital
Conditions:
Proton Pump Inhibitors
Deprescription
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Deprescribing is defined as "the process of withdrawal of an inappropriate medication, supervised by a health care professional with the goal of managing the polypharmacy and improving outcomes". Inap...
Eligibility Criteria
Inclusion
- General practitioners (GP)
- • All GP settled in the French region Pays-de-la-Loire having seen more than 100 different patients in the year before baseline, will be eligible.
- Patients
- Aged more than 18 years old
- Affiliated to the French health insurance CPAM
- Treated with PPI\> 300DDD/year in the year before baseline (estimated with reimbursement databases).
- Whose GP is included in the study
Exclusion
- General practitioners (GPs) :
- • Participation refusal
- Patients
- Participation refusal
- Patients at risk of gastroduodenal lesions i.e. treated with nonsteroidal anti-inflammatory drugs (NSAIDs) and over 65 years old or treated with either corticosteroids or anticoagulants or platelet aggregation inhibitors
- Patients under legal protection
Key Trial Info
Start Date :
September 19 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 19 2023
Estimated Enrollment :
25000 Patients enrolled
Trial Details
Trial ID
NCT04513834
Start Date
September 19 2022
End Date
December 19 2023
Last Update
April 22 2024
Active Locations (1)
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1
University Hospital
Nantes, France, 44000