Status:

UNKNOWN

Evaluation of Filtering Bleb After Glaucoma Surgery by AS-OCTA

Lead Sponsor:

Zhongshan Ophthalmic Center, Sun Yat-sen University

Conditions:

Trabeculectomy

Eligibility:

All Genders

18-80 years

Brief Summary

When antihypertensive drugs or laser therapy can not reach the target intraocular pressure, trabeculectomy (TRAB) is still the standard surgical method for glaucoma. The scarring of the operative area...

Detailed Description

Glaucoma is a group of optic nerve diseases characterized by progressive and irreversible degeneration of retinal ganglion cells and their axons. Retinal ganglion cells, RGCs is a kind of central nerv...

Eligibility Criteria

Inclusion

  • Those who are over 18 years old and can complete all the tests and examinations.
  • Patients who want to undergo trabeculectomy in accordance with the diagnosis of glaucoma.
  • Intraocular pressure can not be controlled by intraocular pressure lowering drugs and laser therapy (intraocular pressure can not be controlled ≤ 21mmHg).

Exclusion

  • Those with a history of ocular trauma, trabeculectomy within 6 months, eye surgery or eye laser within 3 years.
  • The conjunctival state of the proposed surgical area can not support high-quality imaging (signal intensity \< 6).
  • Postoperative conjunctival hemorrhage or serious complications, including hyphema, malignant glaucoma, endophthalmitis and so on.
  • The condition of the whole body does not support surgery, such as heart disease, mental illness, malignant tumor, etc.
  • After trabeculectomy, glaucoma drug treatment or reoperation was performed.
  • Pregnant, lactating and pregnant women. Those who refuse to sign the informed consent form or voluntarily withdraw from the study due to discomfort or other reasons.

Key Trial Info

Start Date :

September 1 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

August 30 2021

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT04515017

Start Date

September 1 2020

End Date

August 30 2021

Last Update

August 17 2020

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