Status:
UNKNOWN
Whether a Minimal Volume Could Predict Fluid Responsiveness Using Thermodilution by PAC in Septic Shock Patients
Lead Sponsor:
Peking Union Medical College Hospital
Conditions:
Septic Shock
Hemodynamic Instability
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Assessment of fluid responsiveness (FR) is to detect whether patient could benefit from fluid therapy. Mini fluid challenge has been widely used in clinical practice to prevent patients from volume ov...
Detailed Description
Fluid therapy is the cornerstone of septic resuscitation. In recent decade, a restrictive fluid strategy has been applied to shock resuscitation for fewer complications and shorter hospital stays comp...
Eligibility Criteria
Inclusion
- Patients diagnosis of septic shock and is required fluid challenge in the presence of invasive hemodynamic monitoring.
- Patients with hypotension (SBP \<90 mmHg or MAP \<65 mmHg)
- Patients with evidences of tissue hypoperfusion (including but not limited to oliguria, skin mottling, altered mental status, cool peripheries, hyperlactatemia, et al).
Exclusion
- Age less than 18yrs or greater than 80yrs
- Shock is diagnosed with other types of shock
- Known allergy to colloid fluids
- Pregnancy
- Recent participation in another biomedical study.
Key Trial Info
Start Date :
July 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2022
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04515511
Start Date
July 1 2019
End Date
September 1 2022
Last Update
September 3 2020
Active Locations (1)
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1
Li Weng
Beijing, Beijing Municipality, China, 100102