Status:
COMPLETED
Effectiveness of Walking Exercise in Improving Cognitive Function in Older Adults With Mild Cognitive Impairment
Lead Sponsor:
The University of Hong Kong
Conditions:
Mild Cognitive Impairment
Eligibility:
All Genders
50+ years
Phase:
NA
Brief Summary
The increasing prevalence of mild cognitive impairment (MCI) in our rapidly aging population prompts the need for devising effective interventions to prevent the onset of cognitive impairment and dela...
Eligibility Criteria
Inclusion
- Older adults aged ≥ 50 years old;
- Ethnic Chinese;
- Diagnosed with mild cognitive impairment (MCI) under the Mayo Clinic criteria \[8-10\]: 1). Subjective complaint about a decline in cognitive function; 2). Total score in the Hong Kong version of the Montreal Cognitive Assessment is below the 7th percentile of the age- and education-corrected normative data of Hong Kong; 3). The decline in cognitive function does not impair daily functioning, as revealed by getting ≥ 2 marks in every item on the Chinese Lawton Instrumental Activities of Daily Living Scale (4-point Scale).
Exclusion
- Diagnosis of dementia/Alzheimer's disease, or currently using antidementia medication;
- Incapable of participating in physical exercise with major confounding conditions that are known to affect mobility. Specifically designed questionnaires will be used to screen for exclusion criteria including 1). Cannot walk without assistive device; 2). Any serious somatic condition that prevents walking exercise participation.
- History of major diseases e.g. cancer, cardio-/cerebrovascular, neurodegenerative and renal diseases;
- Diagnosis of psychiatric diseases, or currently using psychiatric medication.
Key Trial Info
Start Date :
March 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2021
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04515563
Start Date
March 1 2020
End Date
September 1 2021
Last Update
November 11 2021
Active Locations (1)
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1
Li Kai Shing Faculty of Medicine
Hong Kong, Southern District, Hong Kong