Status:

COMPLETED

PRIMA Intervention for Adults With Mild Cognitive Impairment and Their Caregivers

Lead Sponsor:

Indiana University

Collaborating Sponsors:

National Institute of Nursing Research (NINR)

Conditions:

Mild Cognitive Impairment

Eligibility:

All Genders

18-100 years

Phase:

NA

Brief Summary

The investigators developed and tested the Daily Engagement in Meaningful Activities (DEMA) intervention to improve life satisfaction and health outcomes for patients and caregivers. DEMA is a positiv...

Detailed Description

Approximately 20% of Americans over 65 have mild cognitive impairment (MCI), defined as experiencing more memory problems than normally expected with aging, but no other symptoms of dementia such as i...

Eligibility Criteria

Inclusion

  • Both the MCI patient and caregiver must consent to participate and have a phone at home or daily access to a telephone to be eligible for the study.
  • MCI patients will be eligible, if they:
  • are aged \> 59 years old;
  • able to speak and read English;
  • have both self or informant reported cognitive complaints,
  • have MoCA score = 15 to 25
  • are in the normal range in performance of daily living tasks based on functional impairment absent: a check box of Functional Activities Questionnaire (FAQ) has no score ≥2);
  • Family caregivers (spouse, other family members or friends) will be eligible, if they
  • self-identify as care partner
  • are aged ≥ 18 years old,
  • have primary responsibility for providing unpaid care to an MCI patient, along with monitoring safety and providing social support;
  • are able to speak and read English;
  • are oriented to persons, places, and time (having a 6-item Screener score of 4 or above).

Exclusion

  • MCI patients and family caregivers will be excluded, if the MCI patient or family caregiver dyads participants are:
  • a diagnosed untreated severe major depression, or receiving advanced cancer treatment or hospice care,
  • receiving dialysis,
  • severe hearing loss and no hearing aids,
  • have no access to a telephone
  • the family caregiver has significant cognitive impairment that may hinder participation (6-item MMSE \< 4).

Key Trial Info

Start Date :

December 13 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 20 2025

Estimated Enrollment :

420 Patients enrolled

Trial Details

Trial ID

NCT04515875

Start Date

December 13 2021

End Date

July 20 2025

Last Update

July 31 2025

Active Locations (1)

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1

Indiana University Alzhemier Disease Research Center

Indianapolis, Indiana, United States, 46202