Status:
TERMINATED
Effects of Mode of Contraction on Neuromuscular Fatigue
Lead Sponsor:
Centre Hospitalier Universitaire de Saint Etienne
Conditions:
Volunteers
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Aging is associated with multiple deteriorations of the neuromuscular system. Given the increase in life expectancy, the investigators can now distinguish old adults (\>60 years old) who conserve thei...
Eligibility Criteria
Inclusion
- Belong to a defined age group: young (18 to 35 years old inclusive), old (60 to 80 years old inclusive) and very old (81 to 95 years old inclusive),
- Signed written consent form
- Being affiliated to social security
Exclusion
- Pathology or surgery resulting in a locomotor disorder, within 6 months prior to the study,
- Chronic neurological, motor or psychological pathologies
- Use of neuro-active substances likely to alter cortico-spinal excitability (hypnotics, antiepileptics, psychotropic drugs, muscle relaxants) for the duration of the study.
- Contraindication to magnetic stimulation:
- Cardiac or respiratory insufficiency.
- Cardiac pacemaker.
- Cardiac valve wear and serious cardiovascular diseases.
- Presence of prosthetic material or ferromagnetic foreign bodies in the head.
- Presence of cochlear implants or ocular prosthetic material.
- History of neurosurgical interventions.
- Neurological diseases that may affect brain structures and cognitive abilities (e.g., intracranial tumour, multiple sclerosis, history of stroke or traumatic brain injury).
- History of comitiality, contralateral knee pathology or pathology of the musculoskeletal system.
- Mini Mental State Examination \< 20
Key Trial Info
Start Date :
April 13 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 3 2022
Estimated Enrollment :
65 Patients enrolled
Trial Details
Trial ID
NCT04516538
Start Date
April 13 2021
End Date
June 3 2022
Last Update
October 26 2024
Active Locations (1)
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1
CHU de Saint-Etienne
Saint-Etienne, France