Status:
COMPLETED
Prone Position and Respiratory Outcomes in Non-Intubated COVID-19 PatiEnts The "PRONE" Study
Lead Sponsor:
Johns Hopkins University
Collaborating Sponsors:
Duke University
University of North Carolina
Conditions:
Covid19
Pneumonia, Viral
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The overall objective of this study is to determine whether a positional maneuver (e.g., prone positioning) decreases the need for escalation of respiratory-related care in patients with coronavirus (...
Detailed Description
As the initial outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the disease it causes, coronavirus disease 2019 (COVID-19) has spread beyond Wuhan, China it has become ...
Eligibility Criteria
Inclusion
- Age ≥ 18 years
- COVID-19 positive by nasopharyngeal swab or serostatus
- Use of supplemental oxygen OR respiratory rate ≥ 20
Exclusion
- BMI ≥ 45 kg/m2
- Pregnancy
- Chest tube placement
- Hemodynamic instability with mean arterial pressure \< 60 mmHg
- Thoracic or abdominal wounds
- Chest wall deformities
- Vertebral column deformities that would preclude prone positioning
- Facial trauma or surgery in the last 30 days
- Established diagnosis of interstitial lung disease
- Prior single or double lung transplant
- Surgery for spine, femur, or pelvis in the last 3 months
- Thoracic or cardiac surgery in the last 30 days
- Pacemaker placement last 7 days
Key Trial Info
Start Date :
September 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2021
Estimated Enrollment :
35 Patients enrolled
Trial Details
Trial ID
NCT04517123
Start Date
September 1 2020
End Date
December 31 2021
Last Update
January 13 2022
Active Locations (4)
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1
Johns Hopkins Univeristy
Baltimore, Maryland, United States, 21287
2
University of North Carolina
Chapel Hill, North Carolina, United States, 27514
3
Duke University
Durham, North Carolina, United States, 27710
4
UPMC
Pittsburgh, Pennsylvania, United States, 15213