Status:

COMPLETED

Renal Biomarkers in AKI and COVID-19

Lead Sponsor:

Instituto Nacional de Enfermedades Respiratorias

Conditions:

Coronavirus Infection

Covid19

Eligibility:

All Genders

18-70 years

Brief Summary

Severe pneumoniae related to Coronavirus Disease (COVID-19), had a high in-hospital mortality; this condition are worst in subjects with acute kidney disease (AKI); conditioning increased mortality, d...

Detailed Description

The usefulness of urinary NGAL levels and the platelet / lymphocyte index as predictive markers of AKI in the context of COVID-19 will be studied. These results will allow to propose more appropriate ...

Eligibility Criteria

Inclusion

  • Subjects over 18 years of age.
  • Subjects admitted with a diagnosis of probable SARS-CoV-2 pneumonia.
  • Subjects with a diagnosis of SARS-CoV-2 pneumonia confirmed by Real-time quantitative-Polymerase Chain Reaction (qRT-PCR).
  • Subjects with qRT-PCR negative for SARS-CoV-2, but who meet clinical and radiological criteria for COVID-19, and no other causes have been identified.

Exclusion

  • Pregnant women
  • Incomplete medical records.
  • Elimination criteria:
  • Patients who die within the first 24 hours of entering the institute.
  • Patients discharged for any reason not considered death within the first 48 hours, such as voluntary discharge or transfer to other health institutions.
  • Patients who during their hospitalization report a positive PCR for other non-respiratory viruses without identifying SARS-CoV-2
  • Patients who withdraw their consent

Key Trial Info

Start Date :

June 1 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 30 2021

Estimated Enrollment :

51 Patients enrolled

Trial Details

Trial ID

NCT04517630

Start Date

June 1 2020

End Date

September 30 2021

Last Update

June 6 2024

Active Locations (1)

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Centro de Investigacion en Enfermedades Infecciosas

Mexico City, Mexico, 14060