Status:

COMPLETED

Effectiveness of Treatment With Tofacitinib in Patients With Psoriatic Arthritis in Routine Clinical Practice

Lead Sponsor:

Pfizer

Conditions:

Psoriatic Arthritis

Eligibility:

All Genders

18+ years

Brief Summary

This is a Multinational Study of Tofacitinib in Patients Treated for Psoriatic Arthritis in order to evaluate the effectiveness of treatment with tofacitinib on disease activity, remission, and Qualit...

Eligibility Criteria

Inclusion

  • Patients must meet all of the following inclusion criteria to be eligible for inclusion in the study:
  • Patients aged ≥ 18 years
  • Moderate to severe PsA disease activity diagnosed
  • Patients for whom the physician's decision has been made to initiate treatment with tofacitinib, in usual clinical practice conditions and in compliance with the local label
  • Patients are treatment naïve to tofacitinib on the date of providing informed consent
  • Evidence of a personally signed and dated informed consent document indicating that the patient (or a legally acceptable representative) has been informed of all pertinent aspects of the study
  • Patients on DMARDs must have not had a treatment change in the past 3 months

Exclusion

  • Patients meeting any of the following criteria will not be included in the study:
  • Contraindications according to the Xeljanz® (tofacitinib) Prescribing Information
  • Receipt of any investigational drug within 3 months before study inclusion
  • Patient is pregnant or breastfeeding
  • Recent herpes zoster infection (within past 6 months) or history of severe disseminated herpes zoster infection
  • Active treatment for a malignancy
  • Concomitant treatment with a biological disease-modifying antirheumatic drugs (bDMARD)

Key Trial Info

Start Date :

May 17 2021

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

July 30 2024

Estimated Enrollment :

116 Patients enrolled

Trial Details

Trial ID

NCT04517669

Start Date

May 17 2021

End Date

July 30 2024

Last Update

October 14 2025

Active Locations (41)

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Page 1 of 11 (41 locations)

1

Algemeen Stedelijk Ziekenhuis

Aalst, Belgium, 9300

2

AZ Sint-Jan

Bruges, Belgium, 8000

3

Nova Reuma Społka Partnerska

Genk, Belgium, 3600

4

Sygehus Vendsyssel Hospital

Hjørring, Denmark