Status:
COMPLETED
Blood Volume Assessment in COVID-19 and Bacterial Sepsis
Lead Sponsor:
NYU Langone Health
Collaborating Sponsors:
Daxor Corporation
Conditions:
Covid19
Acute Respiratory Distress Syndrome
Eligibility:
All Genders
18-95 years
Brief Summary
In patients with SARS-CoV-2 or bacterial infection admitted to the intensive care unit (ICU), the state of the intravascular volume, the characteristics of the blood volume components, and the develop...
Detailed Description
Acute respiratory failure related to infection by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), is the main reason for ICU admission in in the majority of patients admitted to the ...
Eligibility Criteria
Inclusion
- Confirmed SARS-CoV-2 or bacterial infection
- Patient admitted to the ICU
- Patient age is between 18 and 95 years
- Patent peripheral or central venous line from which blood draws can be made and through which the 131I bolus can be administered
- Arterial catheter considered indicated by primary team caring for the patient
Exclusion
- Refused informed consent to participate in the study
- Pregnant or possible pregnant women
- Patient unlikely to survive more than 72h
- Patient with life sustaining treatment limitations (use of renal replacement therapy)
- Patient already on or likely to be placed on extra-corporeal membrane oxygenation support within 48h after admission
- Known allergy to iodine or iodinated 131I albumin
- Patients with chronic renal failure requiring renal replacement therapy
Key Trial Info
Start Date :
August 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 9 2023
Estimated Enrollment :
39 Patients enrolled
Trial Details
Trial ID
NCT04517695
Start Date
August 1 2020
End Date
April 9 2023
Last Update
September 21 2023
Active Locations (3)
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1
Uniformed Services University of the Health Sciences
Bethesda, Maryland, United States, 20814
2
NYU Langone Health
New York, New York, United States, 10016
3
Wake Forest Baptist Health
Winston-Salem, North Carolina, United States, 27157