Status:

COMPLETED

A Study of a Non-invasive Glucose Measuring Device in Out-patient Settings

Lead Sponsor:

RSP Systems A/S

Conditions:

Diabetes Mellitus

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This explorative clinical investigation has been launched to collect spectral Raman data paired with validated glucose reference values in persons with diabetes.

Eligibility Criteria

Inclusion

  • Male and female subjects minimum 18 years of age
  • Individuals diagnosed with any type of insulin-dependent diabetes mellitus ≥ 1 year
  • Willing to perform up to 12 finger-pricks during each day of out-patient measurements
  • Signed informed consent
  • For women of childbearing potential: Willing and able to practice FDA approved birth control during the duration of the investigation
  • Subject has a 2.4 GHz wireless internet connection at home (standard in normal routers) to be used in the study

Exclusion

  • For female subjects: Pregnancy or breastfeeding
  • Skin phototype VI categorized by Fitzpatrick scale measured on thenar
  • Subjects not able to understand and read local language
  • Cognitive impairment, or in investigator's opinion, subject is not able to follow instructions provided and as specified in the protocol
  • Subject not able to hold hand/arm steady (including tremors and Parkinson's Disease)
  • Extensive skin changes, tattoos or diseases on right thenar (measurement site)
  • Reduced circulation in right hand evaluated by Allen's test
  • Known allergy to medical grade alcohol
  • Hemodialysis
  • Systemic or topical administration of glucocorticoids at the right hand for the past 7 days or during the study period expected
  • Any disorder, which in the investigator's opinion might jeopardize subject's safety or compliance with the protocol
  • Severe diabetes-related complications such as advanced autonomic neuropathy, kidney disease, foot ulcers, legal blindness, or symptomatic cardiovascular disease as evidenced by a history of cardiovascular episode(s)
  • Dependency from the sponsor or the clinical investigator (e.g. co-workers of the sponsor, the study site, and/ or their families)
  • Subjects currently participating in another study
  • Subjects who have participated in the study IDT-1904-RO/RSP-21 or RSP-19.
  • Incapacity for consent

Key Trial Info

Start Date :

September 24 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 23 2022

Estimated Enrollment :

173 Patients enrolled

Trial Details

Trial ID

NCT04518813

Start Date

September 24 2020

End Date

April 23 2022

Last Update

November 18 2023

Active Locations (1)

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Institut für Diabetes-Technologie, Forschungs- und Entwicklungsgesellschaft mbH an der Universität Ulm

Ulm, Germany, 89081