Status:
UNKNOWN
Role of Vitamin C in Cardiac Vasoplegia After Cardiopulmonary Bypass
Lead Sponsor:
Cairo University
Conditions:
to Study the Effect of Vitamin C Administration on the Amount and the Time of Weaning of Noradrenaline Given Post-operatively to Patients After CPB
Eligibility:
All Genders
25-85 years
Brief Summary
This is a parallel group double-blind, randomized-controlled trial with 1:1 randomization ratio which will be conducted over a period of 6 months to study the effect of vitamin C administration on the...
Detailed Description
Background and Rationale: Cardiac vasoplegia is a known phenomenon after cardiopulmonary bypass (CPB) occurring in up to 44% of patients. Severe forms of such condition refractory to vasopressors are...
Eligibility Criteria
Inclusion
- Patients undergoing cardiac surgeries with CPB having risk factors for cardiac vasoplegia like diabetes mellitus and chronic renal failure.
Exclusion
- Patients who undergo surgeries without cardiopulmonary bypass (off-pump)
- Patients undergoing surgeries for congenital cardiac disease
- Patients performing heart transplantation and combined cardiac surgeries
- Patients with low pre-operative left ventricular ejection fraction (LVEF)
- Patients refusing to participate
- Patients who receive vasopressors other than noradrenaline
Key Trial Info
Start Date :
April 16 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 30 2020
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04519281
Start Date
April 16 2020
End Date
October 30 2020
Last Update
August 19 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Cairo University
Cairo, Egypt, 11956