Status:
RECRUITING
Effect of Olivomed (Olive Extract) on Endothelial, Cardiac and Vascular Function
Lead Sponsor:
University of Athens
Conditions:
Coronary Artery Disease
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Olive extracts are considered to have antioxidant properties. The investigators will study the effect of olive extracts containing hydroxytyrosol (HT)-olivomed and combination of Oleuropein (OL), Hydr...
Detailed Description
30 patients with stable angiographically documented coronary artery disease will be randomized to receive olive extracts with high concentration of hydroxytyrosol (5 mg po twice per day included in Ol...
Eligibility Criteria
Inclusion
- Age \<70 years
- Stable coronary heart disease
- Patients with acute coronary syndrome who have undergone percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG), 2 months must have passed since the incident
- High LDL levels, low HDL, high triglycerides
Exclusion
- Age\> 70 years
- Patient with diabetes
- Patient with hypertension
- Patient with liver disease
- Patient with thyroid disease
- Patient with active malignancy
- Patient with a disease that affects inflammatory markers (rheumatic diseases, etc.)
- Patient with chronic renal failure (creatinine\> 2 mg / dl)
- Patient treated chronically with corticosteroids
- Patient who has joined a weight loss program or any dietary intervention or intensive exercise programme within the previous 2 months or consumes multivitamin preparations with antioxidant properties.
Key Trial Info
Start Date :
December 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2026
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04520126
Start Date
December 1 2020
End Date
August 1 2026
Last Update
May 29 2024
Active Locations (1)
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1
"Attikon" University General Hospital
Athens, Attica, Greece, 12462